This post announces the top three winners from a 600+ submission essay contest on major AI challenges. Jassi Pannu outlines a state-scale plan to end airborne pathogens, Ege Erdil advises growth-focused policies for countries outside the AI supply chain, and Michael Li compares AI labs’ economics to Hong Kong’s MTR model. Each full essay follows the brief winner descriptions.

The article explores startups like Polsia and Thomas that use swarms of AI agents to launch and run businesses with almost no human employees. It shows how most of these AI-created ventures will fail but a small percentage will succeed, mirroring Shopify’s model, and argues investors are banking on that 5% of winners.