Andreessen Horowitz has led a $55 million Series A round in Town, an AI-powered personal assistant that integrates with tools like email, calendar, Slack and docs to learn your workflow and proactively suggest or execute tasks. Founded by ex-Plaid/Dropbox CTO Jean-Denis Greze and ex-Google/Dropbox product lead Tony, Town aims to turn raw AI intelligence into practical leverage by holding deep, ongoing context and automating follow-ups, scheduling and other messy operational work.

a16z led a $35 million Series A for Lassie, which builds AI agents to handle billing, insurance claims, payroll and other back‐office work for dental practices. The founders spent months in dental offices mapping workflows and have already onboarded 700 practices, cutting errors and saving 250,000 labor hours a year. Lassie plans to expand beyond dental into broader small-business automation.

Matthew Gallagher built MEDVi, a telehealth service for GLP-1 weight-loss drugs, using only AI tools and one sibling in under two months. He outsourced medical and logistics functions, automated marketing end-to-end with AI, and drove $400 million in revenue his first year while targeting $1.8 billion next.

10x Science built a platform that uses chemistry-based algorithms and AI agents to interpret complex mass spectrometry data, speeding up protein characterization for drug development. Backed by a $4.8 million seed round, it helps biotechs and pharma quickly validate AI-generated treatment candidates. The startup plans to refine its models and expand offerings by integrating broader cellular data.

Despite the popularity of startup accelerators, 99% fail to meet expectations due to a lack of effective mentorship and experience among their founders. Successful accelerators like Y Combinator thrive because their leaders possess firsthand knowledge of building billion-dollar companies, which is often missing in most programs. The distinction between true accelerators and startup schools is crucial for understanding their impact on startups.