Agentic AI systems, particularly those utilizing large language models (LLMs), face significant security vulnerabilities due to their inability to distinguish between instructions and data. The concept of the "Lethal Trifecta" highlights the risks associated with sensitive data access, untrusted content, and external communication, emphasizing the need for strict mitigations to minimize these threats. Developers must adopt careful practices, such as using controlled environments and minimizing data exposure, to enhance security in the deployment of these AI applications.