Researchers at Temple University have discovered that microglia, the brain's immune cells, can both increase and decrease inflammation, which plays a crucial role in neurodegenerative diseases like Alzheimer's and Parkinson's. Understanding the mechanisms behind this dual behavior could lead to new therapeutic strategies aimed at preserving cognitive function and slowing disease progression.
Researchers at Washington University School of Medicine have discovered that Alzheimer’s disease disrupts the circadian rhythms of plaque-clearing brain cells, affecting the activity of numerous genes related to the disease. The study suggests that correcting these circadian rhythms may offer potential therapeutic strategies to slow disease progression.