The article highlights ten standout design projects and materials from 2025 that prioritize sustainability and innovative uses of biology and technology. Notable examples include the BioHybrid gaming controller, created using a symbiotic culture of bacteria and yeast, which integrates sensors and output components during its growth. This project not only redefines how interactive devices can be manufactured but also suggests a future where technology is grown rather than built, potentially leading to biodegradable devices. Another significant project is the 79th Organ, a prosthetic designed to filter microplastics from the human body. Made from the mycelium of mushrooms, this organ employs enzymes to break down harmful plastics, acting as a detoxification system. The design builds on research about plastic-eating fungi and aims to provide a solution to the growing microplastic problem in our environment. Yamaha's digital piano, made from recycled rare wood, showcases how traditional materials can be reused in innovative ways. The keyboard, crafted from African Blackwood, evolves in color and texture over time, highlighting the beauty of natural materials. Other projects, like the Indikator Sonic Bench, turn human touch into sound, enhancing public interactions, while the NEWRON pen stimulates creativity through its unique design. Each of these projects reflects a broader trend towards integrating ecological awareness and sensory engagement in design.