Crypto is experiencing a phase reminiscent of the 80s-90s fund mania, creating a pressing need for on-chain funds of funds. These structures aim to manage continuous due diligence and smartly rebalance among various managers and strategies. The complexity of modern vaults requires a team of quantitative analysts and advanced tools that operate in real-time. Key responsibilities for these funds include a comprehensive risk management system to monitor all positions across different funds. This serves as a foundation for quants conducting research and analysis. They need to perform quantitative risk checks, which involve assessing conditional value at risk, volatility, and liquidity of tokens. Manager risk involves assessing teams through interviews and maintaining communication for insights into operations. Liquidity oversight is critical, as these funds must remain liquid while navigating concentration risks. Fundamental research is also essential, focusing on protocol audits and identifying potential issues that could trigger rebalances. The article emphasizes that while this is just an initial overview, successful on-chain funds will need to refine their strategies to identify the best underlying assets and produce public research to support their decisions. There's a clear warning that many participants in these vaults lack the knowledge to size investments appropriately or track underlying assets effectively. Fund of Funds services are anticipated to emerge soon, managing billions in assets under management (AUM).